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Open access Oct 2026

Improving data capture of the patient experience for young adults with cancer: A randomized controlled trial of precision electronic patient-reported outcomes in community-based oncology practices (ECOG-ACRIN EAQ202).

431 Background: Patient-reported outcomes (PROs) characterize patient perspectives on symptoms, functioning, and health-related quality of life (HRQOL). Despite rising cancer incidence among young adults (YAs), PROs are underutilized, particularly in NCI Community Oncology Research Program (NCORP) sites, where...

J. Salsman, Feng-Hai Duan, S. Dinner et al. · 0 citations
Clinical trial Sep 2026

Venetoclax added to dose-adjusted EPOCH-R for newly diagnosed double-hit lymphomas: phase 2 results from ALLIANCE A051701, an open-label, randomised, controlled, phase 2-3 trial.

BACKGROUND High-grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6, known as double-hit lymphoma, is a highly aggressive malignancy with poor outcomes after standard chemoimmunotherapy. We aimed to study whether the addition of the BCL2-inhibitor venetoclax to chemoimmunotherapy in patients with doub...

J. Abramson, S. Geyer, Sharmila Giri et al. · 0 citations

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