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Author

S. Díaz-Miranda

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Open access Sep 2026

Age-Stratified Analysis of Blood–Brain Barrier Proteins Identifies Lower Occludin Abundance in the 3xTg-AD Model

Lower occludin abundance is identified as the principal BBB-associated protein alteration in the 3xTg-AD model and exploratory evidence of increased BBB permeability at 3 months is provided.

K. M. Delgado-Minjares, C. Flores-Maldonado, J. Campos-Blázquez et al. · 0 citations
Review Open access Oct 2026

“Morphological, Functional, and Molecular Progression of Blood-Brain Barrier Dysfunction in Alzheimer’s Disease”

Blood-brain barrier (BBB) dysfunction is increasingly recognized as an early pathological event in sporadic Alzheimer’s disease (AD), which represents over 95% of cases. Vascular risk factors and cerebral insulin resistance are considered potential contributors to its initiation. This review synthesizes evidence availa...

Karen León-Arcia, Humberto Martínez-Orozco, Magdalena Guerra-Crespo et al. · 0 citations

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