Tuberculosis (TB) remains one of the leading causes of infectious disease mortality worldwide despite widespread Bacille Calmette-Guérin (BCG) vaccination and decades of control efforts. The limited and variable efficacy of current vaccination strategies, particularly against adult pulmonary disease, highlights the nee...
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to pose a significant global health challenge despite the existence of effective treatments. The only licensed TB vaccine, Bacillus Calmette–Guérin (BCG), offers inconsistent and generally limited protection against adult pulmonary TB. As a result...
This review focuses on druggable functional RNAs and discusses current and emerging technologies, as well as the scope for their potential clinical utility and targeted treatment, and highlights the most studied optimization strategies and delivery systems designed to enhance the efficacy and tissue-specific delivery o...
Barbara Yang, Melina J. Sedano, Karla Perez et al.· Signal Transduction and Targ...· 0 citations
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