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S. Da Silva-Álvarez

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Open access Feb 2026

Spatially fractionated mini-GRID radiotherapy differentially modulates radiation-induced senescence in murine glioma and normal cells.

BACKGROUND Spatially fractionated radiotherapy (SFRT) is an emerging therapeutic strategy that enhances tumor control while reducing normal tissue toxicity. Although conventional radiotherapy is known to induce therapy-induced senescence (TIS), its induction by SFRT-particularly mini-GRID radiotherapy-remains poorly ch...

M. Acuña, M. Prados, S. Da Silva-Álvarez et al. · 0 citations

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