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Author

S. Chamakuri

2 papers indexed here

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Oct 2026

Diastereoselective Synthesis of Tetrahydroquinolines through a Multi-component Aza-Prins-Ritter Reaction Sequence.

A series of substituted tetrahydroquinoline (THQ) derivatives were synthesized via a triflic acid-promoted multicomponent aza-Prins-Ritter reaction of 2-(tosylamino)styrenes with carbonyl compounds and substituted acetonitriles, the latter serving as both solvent and nucleophile. The reaction proceeds under mild condit...

Afton Fults, Moh. Sattar, Sakamuri Sarath Babu et al. · 0 citations
Open access Oct 2026

Design, Synthesis, and Pharmacological Profiling of Serine/Threonine Kinase 33 (STK33) Inhibitors for Nonhormonal Male Contraception

Serine/threonine kinase 33 (STK33) is a male germ-specific nonhormonal contraceptive target that is both genetically and chemically validated. Building on our previously reported reversible male contraceptive inhibitor, CDD-2807, we conducted systematic structure−activity relationship (SAR) and structure−property rel...

A. Ku, H. Ta, Yong Wang et al. · 0 citations

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