Diagnostic classifications based on cognitive, CSF, and PET biomarkers across ADNI cohorts: cross-sectional and longitudinal variability
Alzheimer’s disease and related neurodegenerative disorders exhibit marked clinicobiological heterogeneity, posing challenges for accurate diagnosis, prognosis, and therapeutic development. Using data from multiple cohorts of the Alzheimer’s Disease Neuroimaging Initiative (ADNI), we conducted comprehensive cross-sec...