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Author

S. Capuano

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Sep 2026

Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design.

There is currently no approved vaccine for Shigella spp., a leading cause of diarrhea with increasing rates of antimicrobial resistance. Shigella vaccine development is complicated in part by an incomplete understanding of the structural and molecular determinants of immunity. To address this, we isolated monoclonal an...

Robert M. Gallant, Paul Savarino, Sophia Pulido et al. · 0 citations
Open access Aug 2026

Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection

It is suggested that KIR3DL01+ NK cells contribute to the inhibition of SIV replication during chronic infection, and the feasibility of AAV-vectored antibody delivery for long-term, perhaps indefinite depletion of a lymphocyte subset in a nonhuman primate model is demonstrated.

Kjell Sandstrom, Grace N. Hagedorn, Sean C Robinson et al. · 0 citations

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