An mRNA-lipid nanoparticle vaccine targeting the Plasmodium vivax E140 antigen
Plasmodium vivax (Pv) remains the primary cause of malaria outside Africa, yet no licensed vaccine is available against this pathogen. Here, we evaluate the immunogenicity and protective efficacy of novel vaccines targeting E140, a recently identified multi-stage antigen conserved across Plasmodium species. Lipid nanop...