Author

S. Boral

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Open access Jul 2026

Conformational changes induced in ubiquitin by circular protein-DNA chimeras

The NMR-scale synthesis of circular chimeras of single-and double-stranded DNA with ubiquitin, an essential component of many cellular pathways, is described and the results establish both the promise of this strategy and the need to account for local DNA-protein interactions.

S. Boral, Michael D. Schnebly, D. Gamada et al. · bioRxiv · 0 citations