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AKU eCommons

Elizabeth J. Klemm, S. Shakoor, Andrew J. Page et al. · 0 citations
Open access Jul 2026

Colistin resistance-mediated lipopolysaccharide modification in Klebsiella pneumoniae modulates host inflammatory response

Resistance to the polymyxin antimicrobial colistin in Gram-negative bacteria is associated with a modification of the immunogenic lipid A moiety of the lipopolysaccharide (LPS). Chromosomal and plasmid-borne colistin resistance results in the addition of L-Ara4N and pEtN groups to lipopolysaccharide (LPS), respectively...

A. Dutta, P. Gallagher, Katrien M. J. Sutherland et al. · 0 citations

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