A Comprehensive Review of Lipid-Based Topical Nanocarriers for the Treatment of Atopic Dermatitis.
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease affecting 1-3% of adults and 20% of children. It is characterized by type 2 immune dysregulation and epidermal barrier dysfunction. The pathophysiology involves loss-of-function mutations in the filaggrin gene (FLG), tight junction defects, and al...