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S. Ayton

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Open access Oct 2026

Frontal cortical neuroinflammation and circulating biomarkers following cardiopulmonary bypass in sheep

Cerebral hypoxia and neuroinflammation have been implicated in neurocognitive disorders following cardiac surgery, but their postoperative trajectory and relationship with circulating biomarkers are poorly defined. We investigated cerebral tissue oxygenation, neuroinflammation, and plasma biomarkers of neurodegeneratio...

T. Furukawa, A. Jufar, A. Trask-Marino et al. · 0 citations
Open access Oct 2026

Primary care determinants for timely diagnosis of dementia.

OBJECTIVE To identify actions of primary care physicians (PCPs) that influence referral to specialist assessment for dementia from the perspective of people with symptoms of dementia and/or their significant others. DESIGN A descriptive qualitative design was used, involving 33 semistructured interviews that explored...

Hannah Gulline, Sarah Carmody, Amelia Bevins et al. · 0 citations
Review Open access Sep 2026

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

This review surveys recent advances in engineering LNPs that traverse the blood–brain barrier (BBB), evade innate immune surveillance, and achieve cell‐selective expression in the ageing brain and outlines a translational roadmap for brain applications.

A. Belaidi, Denzil Furtado, Francesca M. Alves et al. · 1 citation

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