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S. Authier

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Open access Aug 2026

Integrating New Approach Methodologies and Artificial Intelligence to Advance Central Nervous System Toxicity Prediction: Lessons from Preclinical and Clinical Case Studies.

Central nervous system (CNS) toxicities remain a major cause of drug attrition and represent a persistent challenge in predicting neurological risk during drug development. Limitations in the predictive resolution and translational relevance of conventional nonclinical paradigms contribute to uncertainty in identifying...

Mamta Behl, Fiona S Daly, H. Hogberg et al. · 0 citations

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