Author

S. Arumugam

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Open access Aug 2026

Targeting IDH-driven Oncometabolism in glioblastoma: a computational approach for the identification of potential inhibitors

I1Hit1 and I2Hit1 are highlighted as novel therapeutic compounds with efficient IDH-target inhibition to address epigenetic modification in GBM, and further experimental validation of these compounds is required to demonstrate potential inhibitors of IDH-driven metabolism in GBM.

Nivedhitha Tamilazhagan, S. Arumugam · Frontiers in Bioinformatics · 0 citations