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S. Akkoç

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Open access Oct 2026

Effects of a Benzimidazolium Salt on Colorectal Cancer Cells: Involvement of Apoptosis and Autophagy

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, necessitating the identification of novel small molecules capable of targeting multiple survival pathways. In this study, the antiproliferative potential of dds benzimidazole-palladium (Pd) complexes was evaluated across breast cance...

Mustafa Çakır, E. Acikgoz, B. Kuzu et al. · 0 citations
Open access Oct 2026

Synthesis and Cytotoxic Activity of 1,3‐Selenazole‐2‐Amine Derivatives With Computational ADMET Profiling

A set of newly developed 1,3‐selenazole‐2‐amine derivatives (1–4) was prepared via a modified Hantzsch‐type cyclization of appropriately substituted α‐bromoacetophenones with selenourea under reflux conditions. The synthesized compounds were tested for cytotoxic activity in HT‐29 (colon cancer), MCF‐7 (breast cancer),...

G. Dilek, S. Akkoç · 0 citations

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