Author

S. Abdel-Ghany

3 papers indexed here

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Open access Aug 2026

Targeted Folate-Chitosan Nanoformulations of Quercetin and Coriandrum sativum Reprogram Breast Cancer Hallmarks by Silencing Stemness, Cell Cycle, Angiogenic, and Metastatic Networks

Folate-functionalized chitosan nano-formulations significantly enhanced the anticancer efficacy of quercetin and Coriandrum sativum seed extract through improved targeted delivery, potent antiproliferative, anti-angiogenic, and pro-apoptotic activities, together with favorable modulation of multiple molecular pathways...

Nariman Nabil, Hussein Sabit, J. Almulhim et al. · Pharmaceuticals · 0 citations

Review Open access Aug 2026

Cancer-associated adipocytes: metabolic reprogramming, crosstalk and therapeutic implications in tumor progression

This review synthesizes how CAAs and adipose dynamics drive oncogenesis, progression and therapeutic failure and highlights actionable nodes within the adipose–tumor axis for precision oncology.

Jin-Min Shi, S. Abdel-Ghany, Mariam M Abdelfattah et al. · Signal Transduction and Targ... · 1 citation

Review Open access Sep 2026

Epigenetic Plasticity in Triple-Negative Breast Cancer: Mechanisms of Therapy Resistance, Biomarkers, and Therapeutic Vulnerabilities

Overall, epigenetic plasticity represents both a major driver of TNBC resistance and a therapeutically exploitable vulnerability, provided those future strategies account for tumor heterogeneity, adaptive cell-state transitions, biomarker-guided patient selection, and combination-based treatment design.

A. Alaa, Salma A. B. El-Din, Mohannad A. Farrag et al. · Biomedicines · 0 citations