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S A S Abdullah

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#protein folding Open access Aug 2026

SIRT1 deacetylates GAPDH to drive microglial glycolysis and neuroinflammation.

SIRT1–GAPDH signaling represents a post-translational axis linking sirtuin activity directly to glycolytic enzyme function, distinct from SIRT1's traditional transcriptional roles and serving as a viable molecular checkpoint in microglial immunometabolism.

Chou-Yi Hsu, I. Sapaev, O. Nematov et al. · 0 citations

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