Synthesis, Characterization and Antidiabetic Studies of Sulfonamide Derivatives
The treatment of 4-Amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide (1) with substituted aromatic aldehydes and ketones in absolute ethanol with 2-3 drops of glacial acetic acid as a catalyst under reflux conditions afforded Schiff bases of sulfonamide derivatives (1a-1f) with yields ranging from 84% to 95%. Detailed...