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Ryosuke Ito

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Open access Aug 2026

K+-Selective Compaction of Flexible Ionophore PF1022A: Conformational Landscapes of Alkali Metal Complexes.

The natural cyclic octadepsipeptide ionophore PF1022A (PFA) selectively transports physiologically relevant K+ over Na+ across lipid membranes; however, its underlying structural mechanism remains unclear. Here, variable-temperature ion mobility mass spectrometry and theoretical calculations revealed the conformational...

Shunsuke Kamioka, Ryosuke Ito, K. Ohshimo et al. · 0 citations

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