Carbon dots (CDs) have emerged as promising electrochemiluminescence (ECL) emitters for biosensing due to their low toxicity, facile synthesis and modification, and good biocompatibility. However, most of the reported CDs require a more negative ECL trigger potential than -1.5 V vs Ag/AgCl, which not only induces undes...
Rongfang Li, Guomin Yang, Fang-Xin Hu et al.· Analytical Chemistry· 0 citations
To overcome low strand utilization and slow kinetics in traditional entropy-driven DNA circuits, herein we propose a novel responsive reconstruction-driven Autocatalysis DNA Circuit (rrADC) for constructing highly sensitive electrochemical biosensor. Using 17β-estradiol as a targeted ligand, the specific ligand-aptamer...
An ultrasensitive electrochemical aptasensor for SW620 cell-derived exosomes (SW620-Exo) that integrates aptamer proximity ligation, a three-dimensional DNAzyme walker, an integrated sequential activation DNA (ISD) molecular circuit, and highly catalytic BiFeO3/g-C3N4 heterojunction nanosheets is reported.
Ming Yuan, Xin-Mei Song, Xia Li et al.· Analytical Chemistry· 0 citations
An adaptive dynamic DNA system that undergoes target-triggered dynamic reconfiguration in the presence of miRNA-21 or miRNA-221 provides a highly precise and robust platform for multiplexed biomarker analysis in complex biological samples.
Jie Zhou, Yu-Wei Wu, Ya-Qin Chai et al.· Biosensors & bioelectronics· 0 citations
Abstract Selective and tunable regulation of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a activity enables on-demand control, yet current strategies remain hindered by nonspecific regulation and limited tunability. Inspired by proximity effect, we present a Cas-regulation-targeting chimera...
