Open access
Sep 2026
Neutrophil extracellular traps delivering lactylated S100a9 aggravate neuronal cuproptosis by regulating Ttr/Commd1/Atp7b axis after traumatic brain injury
A novel pathway wherein NETs, via delivery of S100a9K26la, drive neuronal Ttr overexpression is identified, ultimately triggering neuronal cuproptosis and exacerbating secondary injury after TBI.
Jian-Ye Xu, Xu Zhang, Yang Liu et al.
· Redox Biology · 0 citations