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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Rung-Yi Lai

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Review Open access Sep 2026

Beyond native reactivity: radical SAM enzymes as platforms for new-to-nature chemistry

Radical S-adenosylmethionine (rSAM) enzymes constitute one of the largest and most versatile enzyme superfamilies in biology, catalyzing diverse radical-mediated reactions essential for metabolism, cofactor biosynthesis, nucleic acid modification, and natural product formation. Central to their chemistry is the reducti...

Xu-Xue Liu, Xiang-Yang Gao, Sasipa Booranamonthol et al. · 0 citations
Sep 2026

A Second-Shell Mutation Preorganizes HpnG for Broad-Scope Nucleoside Transglycosylation

Nucleoside analogues are important therapeutic scaffolds, but their synthesis is often protecting-group-intensive. Purine nucleoside phosphorylases offer a mild enzymatic alternative, yet broad substrate accommodation does not necessarily lead to productive glycosyl transfer. Here, we repurposed HpnG, a hopanoid-asso...

Xu-Xue Liu, De Yang, Rung-Yi Lai et al. · 0 citations

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