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Author

Runjiang Song

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Aug 2026

Carbamate-Modified Pyrido[1,2-a]pyrimidinones: Design and Synthesis of Insecticides with High Efficacy and Low Bee Toxicity.

Megoura crassicauda, a sap-feeder on legumes, remains a persistent threat, yet current control depends largely on neonicotinoids that pose serious risks to beneficial pollinators. We herein describe a set of new pyrido[1,2-a]pyrimidinone derivatives bearing a carbamate moiety attached via a methylene spacer at the 2-po...

Qing-Qing Ma, Shang Wu, Luo-Man Zhang et al. · 0 citations
Jul 2026

Novel Pyrazole-Quinoxaline Conjugates as Potent HPPD-Inhibiting Herbicides with Notable Crop Safety.

4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a vital target for herbicide development. A series of pyrazole-quinoxaline conjugates were designed and synthesized via scaffold hopping and structural optimization. Bioassays revealed that B9 exhibited potent inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) w...

Li Liu, Mei Zhang, Lingling Wang et al. · 0 citations

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