The development of organic photocatalysts holds considerable promise for the oxidation of NADH, thereby disrupting the NADH/NAD+ equilibrium, modulating redox homeostasis, and enhancing treatment of hypoxic tumors. However, there is still a lack of organic photocatalyst which could respond to near-infrared light. Herei...
This study designed and prepared a novel type I/II dual-mechanism and oxygen-independent aryl free radical combined oxime ester based photoinitiator (DPTO) for treating bacterial infections and enhancing wound healing and validates the substantial potential of DPTO in photodynamic antibacterial therapy.
A novel lipid droplet-targeted aggregation-induced emission photosensitizer CTC was designed and synthesized, providing a novel candidate and new insight for safe and efficient breast cancer PDT.
Yukun Zhang, Lidong Deng, Qi-Yan Li et al.· Bioorganic chemistry (Print)· 0 citations
Thiophenol (PhSH) is a highly toxic aromatic thiol endangering ecosystems, food safety, and human health. Traditional detection methods are limited by instrument dependence and inability for real-time imaging. This study developed a red-emitting fluorescent probe, TTCP-DN, based on the PET mechanism. The probe employs...
Yukun Zhang, Xiaoli Li, Rui-Yuan Liu et al.· Food Chemistry· 0 citations
A multifunctional composite hydrogel (GelDA/OPL) with excellent adhesion, self-healing properties, injectability, and photothermal antibacterial activity through Schiff base crosslinking between dopamine-modified gelatin (GelDA) and oxidized pullulan (OPL) is constructed.
Chen Zhang, Surui Yang, Zhi Xu et al.· Journal of materials chemist...· 0 citations
Cerium molybdate-doped polyaniline nanoparticles are developed to enable a synergistic combination of photothermal therapy (PTT) and CDT, thereby triggering immunogenic cell death (ICD) and enhancing antitumor immunity and presenting a robust nanoplatform integrating chemodynamic and photothermal therapies for potent c...
