Author

Ruiping Wang

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Open access Aug 2026

Pharmacologic Inhibition of SOX9-CDK4 by CYD-4-61 Impairs Gastric Adenocarcinoma Growth and Amplifies Anti-PD-1 Response.

Findings identify the BAX-SOX9-CDK4 axis as an important mechanism contributing to the antitumor activity of CYD-4-61 and provide a strong preclinical rationale for its further development as a therapeutic strategy for aggressive GAC.

Gengyi Zou, Katsuhiro Yoshimura, Yibo Fan et al. · Cancer Letters · 0 citations