Open access
Jul 2026
Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression
ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication. In this study, circular RNA circAP2B1 is identified as a critical regulatory molecule that is markedly upregulated in ESCC tissues and patient serum and strongly ass...
Yi-Ru Wang, Gang Feng, You-Yu Wang et al.
· Advancement of science · 0 citations