Open access
Aug 2026
β-carboline derivative Z86 alleviates pulmonary fibrosis via suppressing TGF-β/Smad signaling
This work identified isopropyl 9-ethyl-1-(naphthalen-1-yl)-9H-pyrido[3,4-b] indole-3-carboxylate (Z86) as a promising bioactive agent against Bleomycin induced pulmonary fibrotic mice with the lung abnormalities including histological alteration, accumulation of ECM, as well as markers of EMT were all relieved upon Z86...
Yu-yang Wang, Shao-hua Zhang, Rong Geng et al.
· Natural Products and Biopros... · 0 citations