Author

Ruiya Xiao

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#machine learning Preprint Sep 2026

Democratizing Clinical Tumor Whole Genome Sequencing: 18-hour End-to-end Analysis via Trillion-parameter Large Language Models Locally Deployed on Consumer-grade Hardware

Whole genome sequencing (WGS) is essential for precision oncology, yet its clinical adoption remains limited by prohibitive computational costs and multi-day turnaround times. This work presents a fully localized low-resource framework enabling stable deployment of a trillion-parameter biomedical LLM on a single consum...

Rui-Ya Xiao, Yi-Li Xu · 0 citations

#machine learning Preprint Aug 2026

Deploying DeepSeek 175B Locally on a Single Consumer-Grade RTX 4060 Laptop with 32GB RAM for 200k-Scale Protein-Ligand Virtual Screening

This work validates the engineering feasibility of running industrial-scale trillion-parameter LLM-driven biomedical computing tasks on consumer hardware, establishing a new low-barrier paradigm for AI-powered early stage drug discovery.

Rui-Ya Xiao, Yi-Li Xu · 0 citations