Upregulation of YAP attenuates doxorubicin-induced cardiotoxicity through inhibiting ferroptosis.
BACKGROUND Doxorubicin (DOX) is a widely utilized anthracycline chemotherapeutic agent in clinical settings; however, its application is significantly constrained by the cardiotoxic effects it induces, the underlying mechanisms of which remain inadequately understood. Ferroptosis, a recently identified form of iron-dep...