Cebpb/JAK2/STAT3 signaling pathway mediated M1 macrophage polarization and metabolic rewiring drive COPD pathogenesis.
Chronic obstructive pulmonary disease (COPD) is asyndrome characterized by airflow limitation, and its pathogenesis is not fully understood. This study intends to conduct a systematic analysis of the key cellular and metabolic remodeling mechanisms involved in the occurrence and development of COPD. A murine COPD model...