Author

Rui-qi Liao

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Review Aug 2026

Cellulose- and lignin-based smart hydrogels for barrier-adaptive delivery of fragile biotherapeutics: Molecular design, activity preservation, and translational considerations.

Fragile biotherapeutics-including therapeutic proteins, peptides, antibody fragments, nucleic acids, and extracellular-vesicle therapeutics-are increasingly central to precision medicine, yet their delivery is limited by conformational instability, enzymatic degradation, oxidative damage, interfacial adsorption, and po...

Kai-Lang Mu, Rui-qi Liao, Jun-Li Xie et al. · International Journal of Bio... · 0 citations

Review Jul 2026

Pharmacological targeting of the extracellular cGAMP-ENPP1 axis in cancer immunotherapy: mechanisms, biomarkers, and translational strategies.

The mechanistic basis, pharmacological rationale, and translational challenges of targeting the extracellular cGAMP-ENPP1 axis in cancer are summarized and a biomarker-guided framework incorporating cGAMP-generating capacity, ENPP1 expression and enzymatic activity, STING-response competence, and on-treatment pharmacod...

Kailang Mu, Rui-qi Liao, Jun Xie et al. · European Journal of Pharmaco... · 0 citations