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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Rui-Long Liu

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Open access Oct 2026

Crystal structure of the SLF1 tandem BRCT domains in complex with a RPB2-derived peptide.

The tandem BRCT domains in the SMC5/6 complex localization factor 1 (SLF1, SLF1tBRCT) mediate interactions with a phosphorylated region in Rad18 and interaction targets the SMC5/6 complex to DNA damage sites for repair. Whether SLF1tBRCT mediate interactions with additional proteins is unclear. In this study, we search...

Pu Chen, Fang-Jie Qiu, Wei Huang et al. · 0 citations

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