Humoral immune responses following inactivated COVID-19 vaccine with different booster intervals: a randomized interventional immunogenicity study.
All booster regimens elicited greater binding and neutralizing responses than the two-dose primary series, with peak responses at 1 month post-booster increasing progressively as the interval lengthened (up to 11 months), however, neutralizing activity against Omicron BA.1 was negligible across regimens.