Author

Rui-Fu Yang

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Open access Oct 2026

Nicotinamide Mononucleotide Does Not Prevent Cardiac Hypertrophy but Attenuates Cardiac Stress and Remodeling Markers in Mice Exposed to Intermittent Normobaric Hypoxia

Background: Nicotinamide mononucleotide (NMN) is a naturally occurring, biologically active nucleotide that serves as a crucial NAD+ precursor in various physiological conditions. Although intermittent hypoxia is known to substantially induce various health problems, whether NMN protects against injury induced by inter...

Zhen Wang, Ming-Xuan Wang, Jing-Ling Guo et al. · Nutrients · 0 citations

Open access Sep 2026

Real-time tracking of Yersinia pestis infection dynamics using a near-infrared fluorescent protein labeling system

ABSTRACT Live imaging is essential for elucidating dynamic infection processes. Here, we developed a near-infrared fluorescent protein (NIR-FP)-based labeling strategy that enables integrated visualization of bacterial behavior in both cellular and animal infection models. Using Yersinia pestis as a model pathogen, we...

Yi-Qian Wang, Tong Wang, Hong-Yan Chen et al. · Microbiology spectrum · 0 citations

Open access Jul 2026

A prehistoric East-Asian Yersinia pestis genome and a ~5.3 ka trans-Eurasian expansion of plague

Mapping variation onto the deep phylogeny showed that the basal stem of the LNBA⁺ lineage is the only one of the seven deep phases examined to show significant enrichment of disruptive genomic remodeling relative to the genome-wide background distribution of mutation categories, consistent with an early episode of adap...

Bing Sun, Yarong Wu, Da-Xuan Zhang et al. · Nature Communications · 0 citations