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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Rui-Bo Guo

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Open access Oct 2026

Microenvironment-Triggered Sequentially Targeted Micelles for Dual Regulation of Macrophages and Fibroblast-Like Synoviocytes via ROS-Responsive Rg1 Release and HAP-1-Mediated Celastrol Delivery in Rheumatoid Arthritis Therapy.

Introduction Excessive proliferation of invasive fibroblast-like synoviocytes (FLS) and persistent synovial inflammation inevitably drive the pathological progression of rheumatoid arthritis (RA). A drug delivery system enabling dual regulation of macrophages and FLS is highly desirable for RA treatment. Methods We f...

Ya-Ni Zhang, Rui-Bo Guo, Ying Zheng et al. · 0 citations

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