Review
Open access
Aug 2026
Single-cell and spatial omics of metabolic-immune ecosystems in prostate cancer: from androgen signaling to therapy resistance
This review synthesizes single-cell and spatial omics evidence for metabolic-immune ecosystems in prostate cancer, emphasizing the transition from androgen dependence to castration resistance, lineage plasticity, metastatic niche adaptation, and therapy resistance.
Rui-Ang Wang, Yi-Fan Li, Xiaoxiang Wang
· Frontiers in Immunology · 1 citation