Review
Open access
Sep 2026
THE ROLE OF CELECOXIB-MEDIATED COX-2 INHIBITION IN MODULATING NEUROINFLAMMATION IN HUMANS: A REVIEW
Peripheral nerve injury triggers a complex cascade of neuroinflammatory events that are essential for initiating regeneration but can become detrimental when prolonged. Cyclooxygenase-2 (COX-2) and its primary product prostaglandin E2 (PGE2) are rapidly upregulated at the injury site by Schwann cells, macrophages, and...
O. Emeka-Obi, C. Ezegbe, Ezinne C. Okorafor et al.
· Universal Journal of Pharmac... · 0 citations