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Rucheng Yao

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Open access Jul 2026

PDIA6 exacerbates hepatocellular carcinoma via enhancing proteasome-dependent degradation of AKAP12.

This study experimentally validated that PDIA6 promotes the proliferation and metastasis of HCC cells and uncovered the HCC-promoting mechanism of the PDIA6-AKAP12-Wnt signaling axis and highlights its great potential for the development of therapeutic targets in HCC.

Rucheng Yao, Yuhan Yin, Xiaosong Li et al. · 0 citations

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