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Ru-Xi Chang

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Open access Sep 2026

Radiosynthesis and preclinical evaluation of 4-N-[¹⁸F]FDG-PBA as a novel PET tracer for tumor imaging

Conventional [¹⁸F]FDG exhibits inherent drawbacks in liver tumor imaging, especially high physiological uptake in normal hepatic tissues, which severely compromises the diagnostic accuracy of hepatic tumors. To address these limitations, we synthesized a novel tracer, 4-N-[¹⁸F]FDG-PBA, via conjugation of [¹⁸F]FDG...

Wei-Xuan Dong, Cong Shen, Ru-Xi Chang et al. · 0 citations

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