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Roxanna Altus

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Open access Oct 2026

Consecutive waves of NODAL inhibition are required for epiblast patterning

The mouse genome encodes two Lefty genes that antagonize NODAL signaling to break symmetry during gastrulation. Despite their central regulatory role, accurately describing and comparing their embryonic function remains unclear. Here, we generated high replicate powered single-cell transcriptional atlases of Lef...

Min-Ming Wang, T. Hou, JoAnne Villagrana et al. · 0 citations

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