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Rou-Gang Xie

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Open access Aug 2026

Peripheral Nerve Injury Induces an Interferon-Responsive State Centered on Satellite Glial Cells in the DRG That Sustains Neuropathic Pain Through STAT1 and CXCL10 Signaling

Highlights What are the main findings? SNI induces a distinct STAT1-associated IFN SGC population in the DRG, characterized by increased CXCL10 expression. This SGC inflammatory program is associated with sensory-neuron hyperexcitability and pain hypersensitivity. Local STAT1 inhibition or CXCR3 blockade alleviates pai...

Wen-Chao Hu, Fu-Tai Wang, Zi-Yi Niu et al. · 0 citations

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