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Rosemeri Alexandre Batalha de Azevedo

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Open access Jul 2026

CEREBROVASCULAR DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, CHANGES IN THE DIAGNOSTIC PROFILE, AND SOCIODEMOGRAPHIC INEQUALITIES, 2010–2024

Objective: To analyze temporal trends in cerebrovascular disease mortality in Brazil, considering changes in the diagnostic profile, sociodemographic characteristics, place of death, and regional distribution from 2010 to 2024. Methods: This was a nationwide ecological time-series study using data from the Mortality Information System (SIM/DATASUS). Deaths classified under codes I60 to I69 of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using absolute and relative frequencies and sex ratio. Results: A total of 1,526,062 deaths from cerebrovascular diseases were recorded, with a 4.1% increase between the first and last five-year periods. Unspecified stroke (I64) remained the leading cause, although its share declined from 43.0% to 33.5%. Conversely, cerebral infarction (I63) increased from 4.2% to 11.4%, and sequelae of cerebrovascular diseases (I69) from 16.5% to 18.6%, suggesting improved diagnostic specification. Mortality was concentrated among individuals aged 60 years or older, with a slight male predominance, proportional growth among Black and Brown populations, relative increase in the North Region, and hospital predominance. Conclusion: Mortality remains high and unequal, requiring cardiovascular prevention, improved stroke care pathways, rehabilitation, and reduction of regional inequities.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al. · 0 citations
Open access Jul 2026

CHRONIC KIDNEY DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, EPIDEMIOLOGICAL PROFILE, AND REGIONAL DIFFERENCES, 2010–2024

Objective: To analyze chronic kidney disease mortality in Brazil according to temporal trends, epidemiological profile, and regional differences from 2010 to 2024. Methods: This ecological time-series study used data from the Brazilian Mortality Information System (SIM/DATASUS). Deaths whose underlying cause corresponded to code N18 of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), were included. Data were grouped into three five-year periods and analyzed using absolute and relative frequencies and percentage change according to sex, age group, race/skin color, education, marital status, place of death, and macroregion. Results: From 2010 to 2024, 110,375 deaths were recorded, with a 41.46% increase between the first and last five-year periods. Men accounted for more than 57% of deaths, which were concentrated among people aged 60 years or older; this group increased from 72.24% to 77.43%. Black and Brown individuals represented 49.64% of deaths in the last period. Hospitals remained the main place of death, although their share decreased from 85.43% to 80.70%. The Southeast had the largest number, whereas the North showed the greatest proportional increase (88.64%). Conclusion: Chronic kidney disease mortality increased in Brazil, with ageing of deaths, persistent male excess mortality, an increasing share among Black and Brown individuals, and regional differences. The findings indicate the need to strengthen early detection, hypertension and diabetes control, access to nephrology, and integrated care pathways.

Alana Coêlho Maciel, T. Santos, Renato Sarmento dos Reis Moreno et al. · 0 citations