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Clinical trial Oct 2026

Felzartamab plus lenalidomide-dexamethasone versus lenalidomide-dexamethasone for relapsed or refractory multiple myeloma: an open-label, parallel-controlled, randomised, phase 3 trial.

BACKGROUND Complement-dependent cytotoxicity (CDC) of CD38 monoclonal antibodies has been associated with infusion-related reactions and might contribute to reduced clinical efficacy of CDC-reliant CD38 antibodies, particularly in patients with relapsed or refractory multiple myeloma with 1q21+. We aimed to evaluate fe...

Hai-Yan He, J. Shang, Ya-Fei Wang et al. · 0 citations
Open access Sep 2026

Predicting the 3-year overall survival in patients with Waldenström Macroglobulinemia using machine learning algorithms

Waldenström Macroglobulinemia (WM) is a rare, incurable B-cell lymphoma characterized by heterogeneous clinical outcomes. Accurate prognosis prediction is critical for risk-adapted therapeutic strategies. We aimed to develop an interpretable machine learning (ML)-based model to predict the 3-year overall survival (OS...

Xu-Fei Huang, Chun-Lan Zhang, Yi-Rong Zhu et al. · 0 citations

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