Open access
Sep 2026
S100A1 Promotes MDM2‐Mediated KLF15 Ubiquitination to Regulate ID1‐Driven Tubular Injury in Diabetic Kidney Disease
Comparison of single‐cell RNA sequencing data of kidney samples from healthy controls and DKD patients reveals a novel S100A1‐MDM2‐KLF15‐ID1 regulatory axis in DKD pathogenesis and suggests targeting S100A1 might be a potential therapy for proximal tubular injury in DKD.
Zhi-Tao Zeng, Jia-Zhen Shang, Shou-Yu Chai et al.
· The FASEB Journal · 0 citations