Open access
Aug 2026
Epigenetic repression of IL-1β by C1QBP restricts Dectin-1-mediated host defense against murine invasive candidiasis
These findings establish C1QBP as a key checkpoint in a PKCδ-dependent epigenetic pathway that constrains antifungal immunity, highlighting its therapeutic potential for invasive fungal diseases.
Hui Wang, Yi-Heng Yang, Jia-Heng Tang et al.
· Nature Communications · 0 citations