The clinical, histopathological, and immunohistochemical findings in the woman with mild conjugated hyperbilirubinemia with normal aminotransferases and cholestatic enzymes supported the diagnosis of DJS, but confirmation of biallelic involvement requires further segregation or phase analysis.
Li Xiao, Xiao-Wei Zhu, Rong-Rong Dou et al.· Zhonghua yi xue yi chuan xue...· 0 citations
Abstract Uterine leiomyoma (UL) is an oestrogen-dependent tumour, and ERα is closely associated with abnormal proliferation of UL cells. This study used structure-guided virtual screening of a 59,319-member peptide library, followed by molecular docking, MST, MD simulation, MM/PBSA analysis, MTT assays, ERα knockdown,...
Ting Guo, Yan Zhang, Shu-Dan Yang et al.· Journal of Enzyme Inhibition...· 0 citations
Primary biliary cholangitis and Sjögren’s syndrome, not systemic sclerosis, are the most common definitive autoimmune diseases in the large anti-CENP-B-positive patient cohort, supporting their complementary role in clinical phenotyping and diagnostic evaluation.
