Review
Open access
Oct 2026
Case Report: Pediatric osteogenesis imperfecta type 1: a pedigree report and literature review
Osteogenesis imperfecta (OI), also known as “brittle bone disease,” is a congenital disorder typically inherited in an autosomal dominant manner. It is a rare genetic disease caused by abnormal mesodermal development leading to defective collagen formation due to variants in various genes. OI is a hereditary connective...
Rong Rong, Xin-Yu Li, Xu-Han Liu
· Frontiers in Pediatrics · 0 citations