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Romane Guisiano

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Open access Sep 2026

Native Hydrogen/Deuterium Exchange Ion Mobility Mass Spectrometry of Structured DNA Oligonucleotides

IMS is established as an essential tool for complementing HDX/MS in the characterization of structural polymorphism and conformational ensembles in DNA oligonucleotides and can be leveraged to distinguish groups of non-specific cation binding on a given conformational ensemble.

Matthieu Ranz, Romane Guisiano, Eric Largy et al. · 0 citations

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