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Robert Rambo

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Open access Jul 2026

Carbonara: a SAXS-guided seeding framework for exploring protein solution-state dynamics

Carbonara is presented, a framework that uses experimental small-angle X-ray scattering (SAXS) data to predict alternative physically plausible protein conformations and provides a route from static structural models of flexible multi-domain proteins and multimeric assemblies to solution-state ensembles.

Josh McKeown, Cameron Brown, Arron Bale et al. · 0 citations

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