Author

Robert P. Bonin

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Open access Sep 2026

Characterization of the Grin1Q536R/+ mouse: a preclinical model for GRIN1-related neurodevelopmental disorder

The findings reveal that the Q536R/+ variant confers an in vivo phenotype indicative of loss of NMDAR function, particularly deficits in NMDAR-mediated transmission and long-term potentiation.

Megan T. Sullivan, Yuan-Ye Yan, Lyra Vania et al. · bioRxiv · 0 citations

Open access Aug 2026

Therapeutic potential of a novel PPARγ agonist in a mouse model of HIV-associated neurocognitive impairment.

PPARγ could serve as a novel molecular target for the treatment of HIV-associated NCI, with INT131 identified as a promising therapeutic candidate.

Celene Titus, M. T. Hoque, Robert P. Bonin et al. · Brain, behavior, and immunit... · 0 citations